A feeding trial was conducted to evaluate the effects of excess dietary branched chain amino acids (BCAAs), isoleucine (Ile) and leucine (Leu) on the growth performance, feed utilization, and blood parameters of juvenile Nile tilapia (Oreochromis niloticus). Results of the study suggest no upper limits for proteinogenic BCAAs in feeds for Nile tilapia formulated using practical ingredients.